Janet Sinsheimer

Professor of Biostatistics, Biomathematics, & Human Genetics

Tel: (310) 825-3460 & (310) 825-8002

Fax: (310) 825-8685

Room AV-321 CHS & 5357C Gonda

Department of Biostatistics

Department of Human Genetics

UCLA School of Public Health

Los Angeles, CA 90095-1772

E-mail:janet@mednet.ucla.edu

Education

Sc.B. in Chemistry (1979) from Brown University
M.A. in Biochemistry (1985) from Brandeis University, Waltham, MA
M.S. in Biomathematics (1988) from UCLA
Ph.D. in Biomathematics (1994) from UCLA

Research & Interests

My research interests are in the statistical modeling of genetic and evolutionary data. In particular, I have been interested in the inference of evolutionary relationships using nucleotide sequence data and in statistical methods for locating disease genes.

Courses

Biostat M272 (formerly M237A) Winter 2001, 02 & Fall 04, 07, 09, 11 Theoretical Genetic Modeling
Biostat M237 (formerly M237B) Winter 2001, 02, 03, 04, Spring 2006, Winter 09, 11, 13 Applied Genetic Modeling

Recent Publications

Dissecting prenatal, postnatal, and inherited effects: ART and design. J. J. Zhou, S. Pelka, K. Lange, C. G. Palmer, J. S. Sinsheimer. Genet Epidemiol. 35:437-46. (2011)
Comparative analysis of proteome and transcriptome variation in mouse. A. Ghazalpour, B. Bennett, V. A. Petyuk, L. Orozco, R. Hagopian, I. N. Mungrue, C. R. Farber, J. Sinsheimer, H. M. Kang, N. Furlotte, C. C. Park, P. Z. Wen, H. Brewer, K. Weitz, D. G. Camp 2nd, C. Pan, R. Yordanova, I. Neuhaus, C. Tilford, N. Siemers, P. Gargalovic, E. Eskin, T. Kirchgessner, D. J. Smith, R. D. Smith, A. J. Lusis. PLoS Genet. 7:e1001393. (2011)
Detection of Intergenerational Genetic Effects with Application to HLA-B Matching as a Risk Factor for Schizophrenia. E. J. Childs, E. M. Sobel, C. G. S. Palmer, J. S. Sinsheimer. Human Heredity 72:161-72 (2011)
Extinction models for cancer stem cell therapy. M. Sehl, H. Zhou, J. S. Sinsheimer, K. L. Lange. Math Biosci. 234:132-46 (2011)
Female mate preference explains countergradient variation in the sexual coloration of guppies (Poecilia reticulata). K. A. Deere, G. F. Grether, A. Sun, J. S. Sinsheimer. Proc Biol Sci. 279:1684-90 (2012)
Effect of Pre-test Genetic Counseling for Deaf Adults on Knowledge of Genetic Testing. E. E. Baldwin, P. Boudreault, M. Fox, J. S. Sinsheimer, C. G. Palmer. J Genet Couns. 21:256-72 (2012)
QTL Association Mapping by Imputation of Strain Origins in Multifounder Crosses. J. J. Zhou, A. Ghazalpour, E. M. Sobel, J. S. Sinsheimer, K. Lange. Genetics 190:459-73 (2012).
Does history repeat itself? Wavelets and the phylodynamics of influenza A. J. A. Tom, J. S. Sinsheimer, M. A. Suchard. Mol Biol Evol. 29:1367-77 (2012).
Rooting Gene Trees Without Outgroups: Ep Rooting. J. S. Sinsheimer, R. J. Little, J. A. Lake, Genome Biol Evol. 2012 May 16. [Epub ahead of print]